A Pilot Feasibility Study of TNFerade™ Biologic with Capecitabine and Radiation Therapy Followed by Surgical Resection for the Treatment of Rectal Cancer | Zendy

Deborah E. Citrin | Zendy; Kevin Camphausen | Zendy; Bradford J. Wood | Zendy; Martha Quezado | Zendy; John Denobile | Zendy; James F. Pingpank | Zendy; Richard E. Royal | Zendy; H. Richard Alexander | Zendy; Geoffrey Seidel | Zendy; Seth M. Steinberg | Zendy; Yvonne Shuttack | Zendy; Steven K. Libutti | Zendy

Open Access

A Pilot Feasibility Study of TNFerade™ Biologic with Capecitabine and Radiation Therapy Followed by Surgical Resection for the Treatment of Rectal Cancer

Author(s) -

Deborah E. Citrin,

Kevin Camphausen,

Bradford J. Wood,

Martha Quezado,

John Denobile,

James F. Pingpank,

Richard E. Royal,

H. Richard Alexander,

Geoffrey Seidel,

Seth M. Steinberg,

Yvonne Shuttack,

Steven K. Libutti

Publication year - 2010

Publication title -

oncology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.987

H-Index - 98

eISSN - 1423-0232

pISSN - 0030-2414

DOI - 10.1159/000323488

Subject(s) - capecitabine , medicine , radiation therapy , colorectal cancer , tolerability , chemoradiotherapy , toxicity , cancer , surgery , stage (stratigraphy) , gastroenterology , adverse effect , paleontology , biology

The purpose of this pilot study was to evaluate the feasibility and tolerability of weekly intratumoral TNFerade™ injections combined with concurrent capecitabine and radiotherapy in the treatment of patients with locally advanced rectal cancer.

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