Open AccessGenome-Wide Linkage Screen for Systolic Blood Pressure in the Veterans Administration Genetic Epidemiology Study (VAGES) of Mexican-Americans and Confirmation of a Major Susceptibility Locus on Chromosome 6q14.1
Author(s) -
Sobha Puppala,
Dawn K. Coletta,
Jennifer L. Schneider,
Shirley L. Hu,
Vidya S. Farook,
Thomas D. Dyer,
Rector Arya,
John Blangero,
Ravindranath Duggirala,
Ralph A. DeFronzo,
Christopher P. Jenkinson
Publication year - 2011
Publication title -
human heredity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.423
H-Index - 62
eISSN - 1423-0062
pISSN - 0001-5652
DOI - 10.1159/000323143
Subject(s) - blood pressure , locus (genetics) , genetic linkage , linkage (software) , genetics , chromosome , medicine , biology , gene
Hypertension or high blood pressure is a strong correlate of diseases such as obesity and type 2 diabetes. We conducted a genome-wide linkage screen to identify susceptibility genes influencing systolic blood pressure (SBP) and diastolic blood pressure (DBP) in Mexican-Americans from the Veterans Administration Genetic Epidemiology Study (VAGES).