Lipopolysaccharide Increases Plasma Levels of Corticotropin-Releasing Hormone in Rats | Zendy

Miriam Goebel | Zendy; Andreas Stengel | Zendy; Lixin Wang | Zendy; Joseph R. Reeve | Zendy; Yvette Taché | Zendy

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Lipopolysaccharide Increases Plasma Levels of Corticotropin-Releasing Hormone in Rats

Author(s) -

Miriam Goebel,

Andreas Stengel,

Lixin Wang,

Joseph R. Reeve,

Yvette Taché

Publication year - 2010

Publication title -

neuroendocrinology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.493

H-Index - 101

eISSN - 1423-0194

pISSN - 0028-3835

DOI - 10.1159/000322590

Subject(s) - medicine , endocrinology , corticotropin releasing hormone , radioimmunoassay , lipopolysaccharide , adrenocorticotropic hormone , chemistry , basal (medicine) , hormone , peptide hormone , hypothalamus , insulin

Corticotropin-releasing hormone (CRH) is expressed in the brain, immune cells and the gut, where gene expression is upregulated by lipopolysaccharide (LPS) 6 h after injection. Whether these changes are reflected by increased circulating levels of CRH and adrenocorticotropic hormone (ACTH) is unknown.

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