Open AccessAssociations between Brain-Derived Neurotrophic Factor Plasma Levels and Severity of the Illness, Recurrence and Symptoms in Depressed Patients
Author(s) -
Liliana Dell’Osso,
Alessandro Del Debbio,
Antonello Veltri,
Carolina Bianchi,
Isabella Roncaglia,
Marina Carlini,
Gabriele Massimetti,
Mario Catena Dell’Osso,
Chiara Vizzaccaro,
Donatella Marazziti,
Armando Piccinni
Publication year - 2010
Publication title -
neuropsychobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.71
H-Index - 83
eISSN - 1423-0224
pISSN - 0302-282X
DOI - 10.1159/000319946
Subject(s) - brain derived neurotrophic factor , depression (economics) , clinical global impression , psychology , pathophysiology , neurotrophic factors , hamilton rating scale for depression , mood , medicine , rating scale , severity of illness , psychiatry , mood disorders , clinical psychology , major depressive disorder , anxiety , developmental psychology , pathology , receptor , alternative medicine , economics , macroeconomics , placebo
There is increasing evidence that the brain-derived neurotrophic factor (BDNF) is involved in the pathophysiology of mood disorders and that its peripheral levels represent a reliable mirror of its concentration in the brain. The aim of the present study was to measure BDNF plasma levels in patients affected by major depression and to explore the possible relationship between the biological parameter and characteristics of the illness.