Effects of Adenosine A2A and A2B Receptor Activation on Signaling Pathways and Cytokine Production in Human Uroepithelial Cells | Zendy

Susanne Säve | Zendy; Katarina Persson | Zendy

Open Access

Effects of Adenosine A<sub>2A</sub> and A<sub>2B</sub> Receptor Activation on Signaling Pathways and Cytokine Production in Human Uroepithelial Cells

Author(s) -

Susanne Säve,

Katarina Persson

Publication year - 2010

Publication title -

pharmacology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.51

H-Index - 59

eISSN - 1423-0313

pISSN - 0031-7012

DOI - 10.1159/000317068

Subject(s) - adenosine , adenosine receptor , cgs 21680 , agonist , creb , endocrinology , medicine , receptor , biology , microbiology and biotechnology , cytokine , chemistry , biochemistry , transcription factor , gene

adenosine A(2A) and A(2B) receptor subtypes have both been implicated in the modulation of inflammation. We examined adenosine A(2A) and A(2B) receptor expression, signaling pathways and the effect of adenosine A(2A) and A(2B) receptor activation on the uropathogenic Escherichia coli (UPEC)-stimulated IL-8 response in human uroepithelial cells (UROtsa).

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