Breast Milk-Transforming Growth Factor-β<sub>2</sub> Specifically Attenuates IL-1β-Induced Inflammatory Responses in the Immature Human Intestine via an SMAD6- and ERK-Dependent Mechanism
Author(s) -
Samuli Rautava,
N. Nanda Nanthakumar,
Alix DubertFerrandon,
Lei Lü,
Jaana Rautava,
W. Allan Walker
Publication year - 2010
Publication title -
neonatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.399
H-Index - 84
eISSN - 1661-7819
pISSN - 1661-7800
DOI - 10.1159/000314109
Subject(s) - transforming growth factor , mapk/erk pathway , mechanism (biology) , medicine , endocrinology , biology , cancer research , immunology , signal transduction , microbiology and biotechnology , philosophy , epistemology
Breast milk is known to protect the infant against infectious and immuno-inflammatory diseases, but the mechanisms of this protection are poorly understood.
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