Open AccessProtein Microarrays for Cancer Diagnostics and Therapy
Author(s) -
Jimmy Lin
Publication year - 2010
Publication title -
medical principles and practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.426
H-Index - 45
eISSN - 1423-0151
pISSN - 1011-7571
DOI - 10.1159/000312709
Subject(s) - protein microarray , medicine , proteomics , cancer therapy , dna microarray , cancer , computational biology , bioinformatics , biology , gene , genetics , gene expression
In this postgenomic age, cancer will be understood in intricate detail beyond the genomic level. New technologies are emerging that allow global proteomic level characterization, profiling and understanding. One of the most exciting emerging technologies of cancer proteomics is protein microarray. In this review, the different types of protein microarrays are discussed, including the methods, challenges and techniques of each type. Subsequently, the application of these specific methods to cancer diagnosis, prognosis and therapy will be overviewed, providing a general review of current methods, and proposing how protein arrays will help shape the future of oncoproteomics.