Open AccessGene Expression Profiling in Vastus Lateralis Muscle During an Acute Exacerbation of COPD
Author(s) -
Tim Crul,
Dries Testelmans,
Martijn A. Spruit,
Thierry Troosters,
Rik Gosselink,
Ineke Geeraerts,
Marc Decramer,
Ghislaine GayanRamirez
Publication year - 2010
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000303054
Subject(s) - exacerbation , copd , muscle atrophy , medicine , gene expression , gene expression profiling , endocrinology , biology , atrophy , gene , biochemistry
The molecular mechanisms leading to loss in muscle force during an acute exacerbation in COPD patients are unknown. A cross-sectional study was designed to compare the gene expression profile of the vastus lateralis muscle in patients with an acute COPD exacerbation and in stable COPD patients.