Open AccessPharmacokinetic Interaction between Indinavir and Darunavir with Low-Dose Ritonavir in Healthy Volunteers
Author(s) -
Vanitha Sekar,
Éric Lefebvre,
Tine De Marez,
Martine De Pauw,
Els De Paepe,
Tony Vangeneugden,
Richard M. W. Hoetelmans
Publication year - 2010
Publication title -
intervirology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.641
H-Index - 61
eISSN - 1423-0100
pISSN - 0300-5526
DOI - 10.1159/000289341
Subject(s) - darunavir , pharmacokinetics , ritonavir , indinavir , adverse effect , tolerability , medicine , chemistry , pharmacology , human immunodeficiency virus (hiv) , viral load , antiretroviral therapy , immunology
To investigate the potential for a pharmacokinetic interaction between darunavir (DRV, TMC114, Prezista), indinavir (IDV, Crixivan) and low-dose ritonavir (RTV, Norvir).