Reversible Ductus Arteriosus Constriction due to Maternal Indomethacin after Fetal Intervention for Hypoplastic Left Heart Syndrome with Intact/Restrictive Atrial Septum | Zendy

Mélanie Vogel | Zendy; Louise WilkinsHaug | Zendy; Doff B. McElhinney | Zendy; Audrey C. Marshall | Zendy; Carol B. Benson | Zendy; Virginia Silva | Zendy; Wayne Tworetzky | Zendy

Open Access

Reversible Ductus Arteriosus Constriction due to Maternal Indomethacin after Fetal Intervention for Hypoplastic Left Heart Syndrome with Intact/Restrictive Atrial Septum

Author(s) -

Mélanie Vogel,

Louise WilkinsHaug,

Doff B. McElhinney,

Audrey C. Marshall,

Carol B. Benson,

Virginia Silva,

Wayne Tworetzky

Publication year - 2009

Publication title -

fetal diagnosis and therapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.976

H-Index - 60

eISSN - 1421-9964

pISSN - 1015-3837

DOI - 10.1159/000268290

Subject(s) - medicine , ductus arteriosus , constriction , hypoplastic left heart syndrome , cardiology , fetus , hypoplasia , heart disease , surgery , pregnancy , biology , genetics

Fetal cardiac intervention (FCI) has been performed at our center in selected fetuses with complex congenital heart disease since 2000. Most interventions are performed in fetuses with a ductus arteriosus (DA)-dependent circulation. Indomethacin promotes closure of the DA in newborns and in fetal life, a potentially life threatening complication in fetuses with ductus-dependent congenital heart disease.

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