Evidence of Interaction between Type 2 Diabetes Susceptibility Genes and Dietary Fat Intake for Adiposity and Glucose Homeostasis-Related Phenotypes | Zendy

Stéphanie-May Ruchat | Zendy; Cathy E. Elks | Zendy; Ruth J. F. Loos | Zendy; MarieClaude Vohl | Zendy; S. John Weisnagel | Zendy; Tuomo Rankinen | Zendy; Claude Bouchard | Zendy; Louis Pérusse | Zendy

Open Access

Evidence of Interaction between Type 2 Diabetes Susceptibility Genes and Dietary Fat Intake for Adiposity and Glucose Homeostasis-Related Phenotypes

Author(s) -

Stéphanie-May Ruchat,

Cathy E. Elks,

Ruth J. F. Loos,

MarieClaude Vohl,

S. John Weisnagel,

Tuomo Rankinen,

Claude Bouchard,

Louis Pérusse

Publication year - 2009

Publication title -

lifestyle genomics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.542

H-Index - 30

eISSN - 2504-3188

pISSN - 2504-3161

DOI - 10.1159/000259341

Subject(s) - single nucleotide polymorphism , glucose homeostasis , tcf7l2 , endocrinology , medicine , type 2 diabetes , snp , biology , insulin , diabetes mellitus , insulin resistance , genetics , gene , genotype

Genome-wide association studies have led to the identification of several susceptibility genes for type 2 diabetes mellitus (T2DM). The objective of this study was to test the hypothesis that the associations between single nucleotide polymorphisms (SNPs) in these genes and adiposity and glucose homeostasis-related phenotypes are influenced by dietary fat intake.

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