HLA-Antigene bei germinativen Tumoren von verschiedener Lokalisierung

In 41 children with germ-cell tumors differently localised and 301 healthy unrelated subjects, 22 HLA antigens of A and B loci were tested. No statistically significant difference in the frequency of HLA antigens--with exception of a higher frequency of HLA-A28 (14,63% versus 4,32% in the controls, chi 2 = 5,69) before the correction of p value--was found. The cause of the rare associations between the tumors and HLA was discussed.