Phosphate – The Silent Stealthy Cardiorenal Culprit in All Stages of Chronic Kidney Disease
Author(s) -
Mehmet Kanbay,
David Goldsmith,
Ali Akçay,
Adrian Covic
Publication year - 2009
Publication title -
blood purification
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.686
H-Index - 57
eISSN - 1421-9735
pISSN - 0253-5068
DOI - 10.1159/000197562
Subject(s) - hyperphosphatemia , kidney disease , medicine , dialysis , renal function , disease , renal replacement therapy , intensive care medicine
Due to increasing evidence suggesting a link between hyperphosphatemia and cardiovascular disease (CVD), mediated through vascular calcification in patients on dialysis, the following question arises: At what stage of chronic kidney disease (CKD) does the relationship between elevated phosphate levels, vascular calcification and increased cardiovascular mortality begin? Therefore, the purpose of the current study was to critically review the current literature regarding this issue.
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