Open AccessEffects of Histamine H<sub>3</sub> Receptor Activation on the Behavioral-Stimulant Effects of Methamphetamine and Cocaine in Mice and Squirrel Monkeys
Author(s) -
Matthew L. Banks,
Daniel F. Manvich,
Rayna M. Bauzo,
Leonard L. Howell
Publication year - 2009
Publication title -
pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.51
H-Index - 59
eISSN - 1423-0313
pISSN - 0031-7012
DOI - 10.1159/000191473
Subject(s) - stimulant , methamphetamine , meth , pharmacology , amphetamine , squirrel monkey , dopaminergic , dopamine , agonist , psychology , chemistry , receptor , medicine , neuroscience , monomer , organic chemistry , acrylate , polymer
Cocaine and methamphetamine (METH) are two commonly abused drugs that have behavioral-stimulant properties. These stimulant effects are partially mediated by the dopaminergic system. Recent evidence has suggested that the histamine H(3) receptor (H(3)R) may modulate the release of dopamine induced by METH. The aim of the present study was to examine the role of H(3)R in the behavioral-stimulant effects of cocaine and METH in mice and monkeys.