Open AccessThe Protective Effect of Egr-1 Antisense Oligodeoxyribonucleotide on Myocardial Injury Induced by Ischemia-reperfusion and Hypoxia-reoxygenation
Author(s) -
Yanmei Zhang,
GuoMing Shi,
Jinhong Zheng,
Yanqiu Lv,
Ping Gao,
Zhanqin Huang,
Fenfei Gao,
Yanliang Zhou
Publication year - 2008
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000185548
Subject(s) - hypoxia (environmental) , reperfusion injury , ischemia , myocardial ischemia , myocardial reperfusion injury , medicine , cardiology , pharmacology , chemistry , oxygen , organic chemistry
Our previous studies have shown that myocardial ischemia-reperfusion (I/R) injury is related closely with early growth response (Egr)-1 overexpression. The present study is to confirm thoroughly the effects of Egr-1 on the occurrance and development of myocardial I/R injury.