Open AccessPost-conditioning Preserves Glycolytic ATP During Early Reperfusion: A survival Mechanism for the Reperfused Heart
Author(s) -
Francisco Correa,
Noemı́ Garcı́a,
Juan Carlos GallardoPérez,
Liliana Carreño-Fuentes,
Sara Rodrı́guez-Enrı́quez,
Álvaro MarínHernández,
Cecilia Zazueta
Publication year - 2008
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000185547
Subject(s) - glycolysis , oxidative phosphorylation , anaerobic glycolysis , cardiac function curve , mitochondrion , ischemia , anaerobic exercise , medicine , reperfusion injury , iodoacetic acid , endocrinology , conditioning , chemistry , metabolism , biochemistry , enzyme , heart failure , physiology , statistics , mathematics
Glycolytic activity during the transition period from anaerobic to aerobic metabolism has been demonstrated to be critical for heart recovery in isolated reperfused hearts. The purpose of this work was to investigate the relevance of the glycolytic pathway in preserving the cardiac function of post-conditioned hearts.