Open AccessAll-Trans Retinoic Acid Decreases Murine Adipose Retinol Binding Protein 4 Production
Author(s) -
Josep M. Mercader,
Nuria Granados,
M. Luisa Bonet,
Andreu Palou
Publication year - 2008
Publication title -
cellular physiology and biochemistry
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000149815
Subject(s) - retinol binding protein 4 , adipokine , endocrinology , adipose tissue , retinoic acid , medicine , insulin resistance , retinoid , adipocyte , tretinoin , retinol , vitamin , biology , retinoic acid receptor , retinol binding protein , chemistry , insulin , cell culture , genetics
Adipose-derived retinol binding protein 4 (RBP4) might contribute to the development of insulin resistance, and therefore further knowledge of factors regulating it is of interest. Retinoic acid, the acid form of vitamin A, affects the expression of several adipokines related to insulin sensitivity in mice. Here, we sought to investigate its impact on adipose RBP4 production.