Importance of Leukoaraiosis on CT for Tissue Plasminogen Activator Decision Making: Evaluation of the NINDS rt-PA Stroke Study | Zendy

Andrew M. Demchuk | Zendy; Firosh Khan | Zendy; Michael D. Hill | Zendy; Philip A. Barber | Zendy; Brian Silver | Zendy; Suresh Patel | Zendy; Steven R. Levine | Zendy

Open Access

Importance of Leukoaraiosis on CT for Tissue Plasminogen Activator Decision Making: Evaluation of the NINDS rt-PA Stroke Study

Author(s) -

Andrew M. Demchuk,

Firosh Khan,

Michael D. Hill,

Philip A. Barber,

Brian Silver,

Suresh Patel,

Steven R. Levine

Publication year - 2008

Publication title -

cerebrovascular diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.221

H-Index - 104

eISSN - 1421-9786

pISSN - 1015-9770

DOI - 10.1159/000139658

Subject(s) - medicine , leukoaraiosis , intracerebral hemorrhage , placebo , white matter , modified rankin scale , stroke (engine) , tissue plasminogen activator , lesion , magnetic resonance imaging , cardiology , surgery , radiology , ischemic stroke , ischemia , pathology , subarachnoid hemorrhage , mechanical engineering , alternative medicine , engineering

Leukoaraiosis is associated with microhemorrhages on T(2)*-weighted magnetic resonance imaging of the brain. Such hemorrhages have been postulated to be responsible for symptomatic intracerebral hemorrhage (ICH) after thrombolytic treatment. We examined the relationship between small-vessel ischemic disease and symptomatic ICH within the NINDS rt-PA Stroke Study.

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