Open AccessNovel Mechanism for Regulation of Endothelin Synthesis: Role of Extracellular pH
Author(s) -
Peter K. Stricklett,
Kevin A. Strait,
Donald E. Kohan
Publication year - 2008
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000113753
Subject(s) - extracellular , chemistry , messenger rna , transfection , endothelin 1 , biochemistry , microbiology and biotechnology , biology , gene , receptor
Several studies suggest that pH may be an important regulator of renal collecting duct endothelin-1 (ET-1) synthesis; the current study was undertaken to examine this interaction.