Open AccessAll-Trans Retinoic Acid Increases Oxidative Metabolism in Mature Adipocytes
Author(s) -
Josep M. Mercader,
Lise Madsen,
Francisco Felipe,
Andreu Palou,
Karsten Kristiansen,
M. Luisa Bonet
Publication year - 2007
Publication title -
cellular physiology and biochemistry
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000110717
Subject(s) - endocrinology , medicine , lipolysis , retinoic acid , beta oxidation , adipogenesis , lipid metabolism , thermogenin , fatty acid synthase , biology , coactivator , peroxisome , peroxisome proliferator activated receptor , adipose tissue , retinoic acid receptor , fatty acid metabolism , receptor , chemistry , white adipose tissue , metabolism , transcription factor , biochemistry , gene
In rodents, retinoic acid (RA) treatment favors loss of body fat mass and the acquisition of brown fat features in white fat depots. In this work, we sought to examine to what extent these RA effects are cell autonomous or dependent on systemic factors.