Open AccessKidneys, Hearts, Hormones and Immunomodulators: Integrated Understandings
Author(s) -
Adeera Levin
Publication year - 2005
Publication title -
blood purification
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.686
H-Index - 57
eISSN - 1421-9735
pISSN - 0253-5068
DOI - 10.1159/000089436
Subject(s) - context (archaeology) , hormone , kidney disease , medicine , disease , erythropoietin , intensive care medicine , aldosterone , bioinformatics , physiology , biology , paleontology
The biological processes governing vascular endothelial cell health are complex and highly redundant. The mechanisms involved in cell injury and repair remain an area of intense study. This paper attempts to review current knowledge regarding hormones such as vitamin D, erythropoietin and aldosterone within the context of what we understand of the inflammatory cascade. This is not a comprehensive review of vascular biology, and many important details and background information have been omitted due to space and complexity considerations. The integration of exocrine and endocrine functions within the kidney, the intimate relationship of those functions with vascular health, and the clinical observations of high prevalence of cardiovascular disease in chronic kidney disease warrant a better understanding of this area by clinicians and basic researchers.