Open AccessEstrogen Receptor Profiles: Changes in Mouse and Rat Mammary Tumors by Treatment with Selective Estrogen Receptor Modifiers
Author(s) -
Andrea Mariel Actis,
Claudia Cocca,
Alicia Beatriz Gutiérrez,
Máximo Croci,
Elena Rivera,
Rosa Bergoc
Publication year - 2004
Publication title -
medical principles and practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.426
H-Index - 45
eISSN - 1423-0151
pISSN - 1011-7571
DOI - 10.1159/000078320
Subject(s) - raloxifene , medicine , endocrinology , estrogen , selective estrogen receptor modulator , tamoxifen , medroxyprogesterone , estrogen receptor , mammary tumor , medroxyprogesterone acetate , breast cancer , cancer
The aim of this work was to analyze the effect of estradiol (E(2)), medroxyprogesterone and the two selective estrogen receptor modulators (SERMs) (tamoxifen (Tam) and raloxifene (Ral)) on the estrogen receptor (ER) conformers profile performed by size exclusion HPLC in relation to hormone dependence of mammary tumors.