Open AccessCyclosporine or FK506 Decrease Mature Epidermal Growth Factor Protein Expression and Renal Tubular Regeneration in Rat Kidneys with Ischemia/Reperfusion Injury
Author(s) -
Chul Woo Yang,
Seung Hun Lee,
Sun Woo Lim,
Ju Young Jung,
Wan Young Kim,
Hyung Wook Kim,
Bum Soon Choi,
Can Li,
Jung Ho,
Yong Soo Kim,
Jin Kim,
Byung Kee Bang
Publication year - 2002
Publication title -
the nephron journals/nephron journals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.951
H-Index - 72
eISSN - 2235-3186
pISSN - 1660-8151
DOI - 10.1159/000065435
Subject(s) - medicine , kidney , immunostaining , epidermal growth factor , endocrinology , regeneration (biology) , ischemia , reperfusion injury , renal cortex , immunohistochemistry , biology , receptor , microbiology and biotechnology
Epidermal growth factor (EGF) plays an important role in tubular regeneration in kidneys with ischemia/reperfusion (I/R) injury. This study was undertaken to evaluate the influence of cyclosporine A (CsA) or FK506 on mature EGF expression and tubular regeneration in rat kidneys with I/R injury.