Open AccessDoes Cimetidine Improve Prospects for Cancer Patients?
Author(s) -
C.P. Siegers,
Steven Andrèsen,
James P. Keogh
Publication year - 1999
Publication title -
digestion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.882
H-Index - 75
eISSN - 1421-9867
pISSN - 0012-2823
DOI - 10.1159/000007686
Subject(s) - cimetidine , medicine , histamine , cancer , placebo , adjuvant , stimulation , pharmacology , gastroenterology , pathology , alternative medicine
Evidence first appeared in 1988 that cimetidine as an adjuvant may improve the survival of severely ill gastro-intestinal cancer patients when given peri- or postoperatively. Since then, several studies have appeared which suggest an anticancer activity for cimetidine, although few attempts have been made to corroborate their findings in large, placebo-controlled, double-blind studies.