Open AccessAbstract 6042: TNFa co-activates IKK/NF-kB/RELA prosurvival and WEE1-CDC2 G2/M checkpoint signaling and is targetable by WEE1 antagonist AZD1775 in head and neck cancer
Author(s) -
Ramya Viswanathan,
Zhengbo Hu,
Jianghong Chen,
Xinping Yang,
Angel P. Huynh,
Paúl E. Clavijo,
Yi An,
Yvette Robbins,
Christopher Silvin,
Clint Allen,
Anthony Saleh,
Zhong Chen,
Carter Van Waes
Publication year - 2020
Publication title -
cancer research
Language(s) - English
Resource type - Conference proceedings
SCImago Journal Rank - 1.055
H-Index - 84
eISSN - 1538-7445
pISSN - 0008-5472
DOI - 10.1158/1538-7445.am2020-6042
Subject(s) - wee1 , cancer research , iκb kinase , cyclin dependent kinase 1 , kinase , biology , tumor necrosis factor alpha , nf κb , cancer cell , head and neck squamous cell carcinoma , phosphorylation , cell cycle , chemistry , signal transduction , apoptosis , cancer , microbiology and biotechnology , immunology , biochemistry , head and neck cancer , genetics