Open AccessAbstract 462: The mutated chromatin modifier gene, H3F3AK27M, is a druggable target of DNA hypomethylating agents in pediatric high-grade glioma
Author(s) -
Hemant Gujar,
Lian Zhang,
Hongtao Li,
Hitoshi Otani,
Daniel J. Weisenberger,
Anat ErdreichEpstein,
Gangning Liang
Publication year - 2020
Publication title -
cancer research
Language(s) - English
Resource type - Conference proceedings
SCImago Journal Rank - 1.055
H-Index - 84
eISSN - 1538-7445
pISSN - 0008-5472
DOI - 10.1158/1538-7445.am2020-462
Subject(s) - histone , dna methylation , biology , epigenetics , hypomethylating agent , cancer research , chromatin immunoprecipitation , glioma , chromatin , histone h3 , ezh2 , mutation , methylation , gene , promoter , genetics , gene expression