Open AccessAbstract 1588: PEGylated recombinant human hyaluronidase, PEGPH20, significantly enhances the anti-tumor activity of the combination of focal adhesion kinase Inhibitor and anti-PD-1 antibody by targeting CXCR4-expressing myeloid cells in a murine model of PDAC
Author(s) -
Arsen Osipov,
Jianxin Wang,
Shiqi Li,
David Choi,
MacKenzie Henderson,
Jonathan A. Pachter,
Jisook Lee,
Dan Maneval,
Lei Zheng,
Alex B. Blair
Publication year - 2020
Publication title -
cancer research
Language(s) - English
Resource type - Conference proceedings
SCImago Journal Rank - 1.055
H-Index - 84
eISSN - 1538-7445
pISSN - 0008-5472
DOI - 10.1158/1538-7445.am2020-1588
Subject(s) - cancer research , tumor microenvironment , stromal cell , medicine , immunotherapy , myeloid , immune system , immune checkpoint , metastasis , immunology , cancer