Open AccessAbstract 1037: Orally available small molecule CD73 inhibitor reverses immunosuppression through blocking of adenosine production
Author(s) -
Xiaohui Du,
Brian R. Blank,
Brenda Chan,
Xi Chen,
Yuping Chen,
Frank Duong,
Lori S. Friedman,
Tom Huang,
Melissa R. Junttila,
Wayne Kong,
Todd C. Metzger,
Jared T. Moore,
Daqing Sun,
Jessica Sun,
Dena Sutimantanapi,
Natalie Yuen,
Tatiana Zavorotinskaya
Publication year - 2020
Publication title -
cancer research
Language(s) - English
Resource type - Conference proceedings
SCImago Journal Rank - 1.055
H-Index - 84
eISSN - 1538-7445
pISSN - 0008-5472
DOI - 10.1158/1538-7445.am2020-1037
Subject(s) - adenosine , pharmacology , in vivo , ex vivo , immunosuppression , adenosinergic , medicine , tumor microenvironment , cancer research , chemistry , immune system , adenosine receptor , biology , in vitro , biochemistry , immunology , receptor , microbiology and biotechnology , agonist