Open AccessAbstract 2908: Mesothelioma phylogeny reveal MTAP as a solitary clonal deletion, exposing vulnerability to the PRMT5 perturbagen, quinacrine
Author(s) -
Sara Busacca,
Lee Brannan,
Apostolos Nakas,
Annabel J. Sharkey,
Chiara Riganti,
David Waller,
Cathy Richards,
Iris C. Salaroglio,
Vladan Milošević,
Peter Wells-Jordan,
Alan P. Dawson,
Michael Sheaff,
John LeQuesne,
Aarti Gaba,
Robert C. Hastings,
Luke Martinson,
Jin-Li Lo,
Amrita Bajaj,
Paul C. Boutros,
Thomas John,
Bibhusal Thapa,
Gareth A. Wilson,
Jacqui Shaw,
Charles Swanton,
Frank Dudbridge,
Edward J. Hollox,
Dean A. Fennell
Publication year - 2019
Publication title -
cancer research
Language(s) - English
Resource type - Conference proceedings
SCImago Journal Rank - 1.055
H-Index - 84
eISSN - 1538-7445
pISSN - 0008-5472
DOI - 10.1158/1538-7445.am2019-2908
Subject(s) - mesothelioma , somatic evolution in cancer , biology , exome sequencing , somatic cell , copy number analysis , exome , oncology , pathology , cancer research , medicine , cancer , genetics , copy number variation , mutation , genome , gene