Open AccessAbstract 2878: CRISPR-Cas9 screens identify the nuclear export factor NXT1 as a novel therapeutic target in MYCN-amplified neuroblastoma
Author(s) -
Clare F. Malone,
Neekesh V. Dharia,
Guillaume Kugener,
Brenton R. Paolella,
Michael Rothberg,
Mai Abdusamad,
Alfredo González,
Nancy Dumont,
Scott T. Younger,
David E. Root,
Francisca Vázquez,
Kimberly Stegmaier
Publication year - 2019
Publication title -
cancer research
Language(s) - English
Resource type - Conference proceedings
eISSN - 1538-7445
pISSN - 0008-5472
DOI - 10.1158/1538-7445.am2019-2878
Subject(s) - crispr , neuroblastoma , biology , druggability , subgenomic mrna , cancer research , gene , computational biology , cas9 , genetics , cell culture