Open AccessAbstract 1911: Bi-directional cross-talk of pancreatic cancer and stellate cells, mediated through CXCR4 and hedgehog pathways, promotes chemoresistance via its effect on gemcitabine metabolism, ROS detoxification and cancer stemness
Author(s) -
Mohammad Aslam Khan,
Girijesh Kumar Patel,
Sanjeev Srivastava,
Sumit Arora,
Haseeb Zubair,
James Elliot Carter,
Bin Wang,
Seema Singh,
Moh’d Khushman,
Anurag Singh
Publication year - 2019
Publication title -
cancer research
Language(s) - English
Resource type - Conference proceedings
SCImago Journal Rank - 1.055
H-Index - 84
eISSN - 1538-7445
pISSN - 0008-5472
DOI - 10.1158/1538-7445.am2019-1911
Subject(s) - gemcitabine , hedgehog , pancreatic cancer , cancer research , hedgehog signaling pathway , stromal cell , cxcr4 antagonist , biology , tumor microenvironment , cxcr4 , gene knockdown , chemistry , microbiology and biotechnology , signal transduction , cancer , chemokine , immune system , apoptosis , immunology , biochemistry , genetics , tumor cells