Open AccessAbstract 1176: Immunogenomic profiling identifies a subgroup of squamous cell lung cancers with immunosuppressed tumor microenvironment and correlates TGF-beta and Wnt/beta-catenin signaling as predictive of low PD-L1 expression
Author(s) -
Marcelo V. Negrão,
Tatiana V. Karpinets,
Jun Li,
Alexandre Reuben,
Cara L. Haymaker,
Kyle G. Mitchell,
Junya Fujimoto,
Chi-Wan Chow,
Edwin R. Parra,
Lorenzo Federico,
Jianhua Zhang,
Ara A. Vaporciyan,
Chantale Bernatchez,
Tina Cascone,
Boris Sepesi,
Ignacio I. Wistuba,
John V. Heymach,
Don L. Gibbons,
Icon Team
Publication year - 2019
Publication title -
cancer research
Language(s) - English
Resource type - Conference proceedings
eISSN - 1538-7445
pISSN - 0008-5472
DOI - 10.1158/1538-7445.am2019-1176
Subject(s) - tumor microenvironment , immune system , cancer research , cd8 , biology , medicine , immunology