Open AccessAbstract 995: Tumor-stroma IL-1β-IRAK4 feedforward circuitry drives tumor fibrosis, chemo-resistance and is associated with poor prognosis in pancreatic cancer
Author(s) -
Daoxiang Zhang,
Lin Li,
Hongmei Jiang,
Andrea WangGillam,
Jinsheng Yu,
Richard D. Head,
JingXia Liu,
Marianna B. Ruzinova,
Kian-Huat Lim
Publication year - 2018
Publication title -
cancer research
Language(s) - English
Resource type - Conference proceedings
eISSN - 1538-7445
pISSN - 0008-5472
DOI - 10.1158/1538-7445.am2018-995
Subject(s) - stroma , cancer research , pancreatic cancer , cancer associated fibroblasts , tumor microenvironment , cancer , cytokine , tumor progression , in vivo , biology , medicine , immunohistochemistry , immunology , tumor cells , microbiology and biotechnology