Open AccessAbstract 4091: Knockout of genes in the DNA mismatch repair pathway to model colorectal cancer hypermutation
Author(s) -
Abbey Jin,
Peter M.K. Westcott,
Olivia Smith,
Amanda M. Cruz,
Mary C. Beytagh,
Tyler Jacks
Publication year - 2018
Publication title -
cancer research
Language(s) - English
Resource type - Conference proceedings
eISSN - 1538-7445
pISSN - 0008-5472
DOI - 10.1158/1538-7445.am2018-4091
Subject(s) - somatic hypermutation , biology , mlh1 , cancer research , dna mismatch repair , msh2 , frameshift mutation , cancer , kras , genetics , mutation , colorectal cancer , gene , b cell , antibody