Open AccessAbstract 4074: Pten haploinsufficiency promotes tumor invasion and carcinogenesis in mouse colon epithelium with Apc deficiency
Author(s) -
Haruki Sada,
Takao Hinoi,
Hiroaki Niitsu,
Mitsugu Kochi,
Naoya Sakamoto,
Kazuhiro Sentani,
Naohide Oue,
Wataru Yasui,
Hideki Otsuka
Publication year - 2018
Publication title -
cancer research
Language(s) - English
Resource type - Conference proceedings
eISSN - 1538-7445
pISSN - 0008-5472
DOI - 10.1158/1538-7445.am2018-4074
Subject(s) - pten , tensin , adenomatous polyposis coli , haploinsufficiency , colorectal cancer , cancer research , genetically modified mouse , biology , loss of heterozygosity , carcinogenesis , familial adenomatous polyposis , transgene , cancer , microbiology and biotechnology , phenotype , allele , gene , genetics , pi3k/akt/mtor pathway , apoptosis