Open AccessAbstract 3184: A secondary mutation inBRAFconfers resistance to RAF inhibition in aBRAFV600E-mutant brain tumor
Author(s) -
Jiawan Wang,
Zhan Yao,
Philip Jonsson,
Amy N. Allen,
Alice Can Ran Qin,
Sharmeen Uddin,
Ira J. Dunkel,
Mary Petriccione,
Katia Manova,
Sofia Haque,
Marc K. Rosenblum,
David Pisapia,
Neal Rosen,
Barry S. Taylor,
Christine A. Pratilas
Publication year - 2018
Publication title -
cancer research
Language(s) - English
Resource type - Conference proceedings
eISSN - 1538-7445
pISSN - 0008-5472
DOI - 10.1158/1538-7445.am2018-3184
Subject(s) - dabrafenib , cancer research , mutation , mutant , cancer , mapk/erk pathway , mek inhibitor , trametinib , kinase , biology , medicine , vemurafenib , genetics , gene , metastatic melanoma