Open AccessAbstract 168: Cancer stem-like properties and drug resistance are dependent on purine synthetic metabolism mediated by the mitochondrial enzyme MTHFD2
Author(s) -
Noriko Gotoh,
Tatsunori Nishimura,
Akinori Nakata,
Shinichi Horike,
Susumu Kohno,
Chiaki Takahashi,
Tomoyoshi Soga,
Arinobu Tojo
Publication year - 2018
Publication title -
cancer research
Language(s) - English
Resource type - Conference proceedings
eISSN - 1538-7445
pISSN - 0008-5472
DOI - 10.1158/1538-7445.am2018-168
Subject(s) - cancer stem cell , gefitinib , cancer research , gene knockdown , cancer , stem cell , cancer cell , biology , purine metabolism , purine , chemistry , apoptosis , biochemistry , enzyme , microbiology and biotechnology , genetics , epidermal growth factor receptor