Open AccessAbstract 145: Pharmacologic inhibition of SIAH2 stabilizes DYRK2 and inhibits survival and self-renewal in chronic myeloid leukemia (CML) leukemic stem cells
Author(s) -
Chun Shik Park,
Shen Ye,
Andrew Henry Lewis,
Koramit Suppipat,
Monica Puppi,
Julie Tomolonis,
Taylor Chen,
Paul Pang,
Toni–Ann Mistretta,
Leyuan Ma,
Michael Green,
Rachel E. Rau,
H. Daniel Lacorazza
Publication year - 2018
Publication title -
cancer research
Language(s) - English
Resource type - Conference proceedings
eISSN - 1538-7445
pISSN - 0008-5472
DOI - 10.1158/1538-7445.am2018-145
Subject(s) - myeloid leukemia , cancer research , leukemia , stem cell , biology , klf4 , k562 cells , haematopoiesis , transplantation , chronic myelogenous leukemia , myeloid , bone marrow , immunology , medicine , microbiology and biotechnology , embryonic stem cell , sox2 , genetics , gene