Open AccessAbstract LB-207: PI3Kγ inhibition suppresses glioblastoma tumorigenicity through disruption of an IL11-STAT3-MYC signaling axis between microglia and glioblastoma
Author(s) -
Jie Li,
Megan M. Kaneda,
Jiangfei Wang,
Kunal Patel,
Johnny Akers,
Valya Ramakrishnan,
Tao Jiang,
Bob S. Carter,
Judith A. Varner,
Clark C. Chen
Publication year - 2017
Publication title -
cancer research
Language(s) - English
Resource type - Conference proceedings
eISSN - 1538-7445
pISSN - 0008-5472
DOI - 10.1158/1538-7445.am2017-lb-207
Subject(s) - microglia , cancer research , glioma , pi3k/akt/mtor pathway , biology , tumor microenvironment , isocitrate dehydrogenase , u87 , stat3 , immunology , signal transduction , microbiology and biotechnology , inflammation , biochemistry , tumor cells , enzyme