Open AccessAbstract 5823: Modulation of the Hippo pathway protein YAP as a mechanism of resistance to MEK inhibition in MAPK hyperactivated neuroblastoma
Author(s) -
Grace E. Coggins,
Lori S. Hart,
Jimmy Elias,
John M. Maris
Publication year - 2017
Publication title -
cancer research
Language(s) - English
Resource type - Conference proceedings
eISSN - 1538-7445
pISSN - 0008-5472
DOI - 10.1158/1538-7445.am2017-5823
Subject(s) - hippo signaling pathway , trametinib , gene knockdown , mapk/erk pathway , cancer research , neuroblastoma , biology , mek inhibitor , cell culture , signal transduction , medicine , microbiology and biotechnology , genetics