Open AccessAbstract 5019: HMGA1 amplifies Wnt signaling and expands the intestinal stem cell compartment to drive premalignant polyposis in transgenic mice
Author(s) -
Lingling Xian,
Dan Georgess,
Li Luo,
Lionel Chia,
Qi-hua Gu,
Tait Huso,
Amy Belton,
David L. Huso,
Andrew J. Ewald,
Linda Resar
Publication year - 2017
Publication title -
cancer research
Language(s) - English
Resource type - Conference proceedings
eISSN - 1538-7445
pISSN - 0008-5472
DOI - 10.1158/1538-7445.am2017-5019
Subject(s) - biology , lgr5 , stem cell , microbiology and biotechnology , carcinogenesis , chromatin remodeling , wnt signaling pathway , cancer stem cell , cancer research , intestinal epithelium , cellular differentiation , chromatin , cancer , epithelium , genetics , signal transduction , gene