Open AccessAbstract 4785: Disrupting redox regulated cancer stem cell state equilibrium by co-inhibition of glycolysis and thioredoxin/glutathione antioxidant pathways
Author(s) -
Ming Luo,
Shang Li,
Michael Brooks,
Evelyn Jiagge,
R. Scott Conley,
Ramdane Harouaka,
Yanjing Zhu,
Sofía D. Merajver,
Douglas R. Spitz,
Max S. Wicha
Publication year - 2017
Publication title -
cancer research
Language(s) - English
Resource type - Conference proceedings
eISSN - 1538-7445
pISSN - 0008-5472
DOI - 10.1158/1538-7445.am2017-4785
Subject(s) - thioredoxin , thioredoxin reductase , glutathione , glycolysis , oxidative stress , chemistry , oxidative phosphorylation , microbiology and biotechnology , cancer cell , mitochondrial ros , ampk , biochemistry , cancer research , biology , phosphorylation , cancer , metabolism , protein kinase a , enzyme , genetics