Open AccessAbstract 3981: The Shc1 scaffold protein simultaneously balances Stat1 and Stat3 activity in breast cancer to promote immune suppression and resistance to immunotherapy
Author(s) -
Ryuhjin Ahn,
Kévin Jacquet,
Marc R. Fabian,
Sidong Huang,
Nicolas Bisson,
Josie UrsiniSiegel
Publication year - 2017
Publication title -
cancer research
Language(s) - English
Resource type - Conference proceedings
eISSN - 1538-7445
pISSN - 0008-5472
DOI - 10.1158/1538-7445.am2017-3981
Subject(s) - kinome , cancer research , immune system , tyrosine , stat1 , immune checkpoint , tumor microenvironment , breast cancer , tyrosine kinase , signal transduction , immunotherapy , receptor tyrosine kinase , phosphorylation , sh2 domain , biology , cancer , medicine , immunology , microbiology and biotechnology , biochemistry