Abstract 1853: Inhibition of mTOR downregulates expression of DNA repair proteins and is highly efficient against BRCA2-mutated breast cancer when combined to PARP inhibition | Zendy

Florence Coussy | Zendy; Rania El Botty | Zendy; Rana Hatem | Zendy; Franck Assayag | Zendy; Ahmed Dahmani | Zendy; Marine Huppé | Zendy; Sophie Chateau Joubert | Zendy; Jean Luc Servely | Zendy; Virginie Bernard | Zendy; Sophie Vacher | Zendy; Berangere Ouine | Zendy; Aurélie Cartier | Zendy; Leanne de Koning | Zendy; Paul Cottu | Zendy; Ivan Bièche | Zendy; Elisabetta Marangoni | Zendy

Open Access

Abstract 1853: Inhibition of mTOR downregulates expression of DNA repair proteins and is highly efficient against BRCA2-mutated breast cancer when combined to PARP inhibition

Author(s) -

Florence Coussy,

Rania El Botty,

Rana Hatem,

Franck Assayag,

Ahmed Dahmani,

Marine Huppé,

Sophie Chateau Joubert,

Jean Luc Servely,

Virginie Bernard,

Sophie Vacher,

Berangere Ouine,

Aurélie Cartier,

Leanne de Koning,

Paul Cottu,

Ivan Bièche,

Elisabetta Marangoni

Publication year - 2017

Publication title -

cancer research

Language(s) - English

Resource type - Conference proceedings

eISSN - 1538-7445

pISSN - 0008-5472

DOI - 10.1158/1538-7445.am2017-1853

Subject(s) - olaparib , pi3k/akt/mtor pathway , pten , cancer research , everolimus , parp inhibitor , protein kinase b , dna repair , breast cancer , biology , cancer , medicine , signal transduction , poly adp ribose polymerase , microbiology and biotechnology , dna , genetics , polymerase

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