Open AccessSingle Daily Dosing of Gentamicin: Pharmacokinetic Comparison of Two Dosing Methodologies for Postpartum Endometritis
Author(s) -
C. Liu,
B. Abate,
M. Reyes,
Bernard Gonik
Publication year - 1999
Publication title -
infectious diseases in obstetrics and gynecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.656
H-Index - 48
eISSN - 1098-0997
pISSN - 1064-7449
DOI - 10.1155/s1064744999000216
Subject(s) - dosing , pharmacokinetics , gentamicin , volume of distribution , medicine , aminoglycoside , trough concentration , elimination rate constant , body weight , endometritis , distribution (mathematics) , anesthesia , urology , pharmacology , antibiotics , chemistry , pregnancy , mathematics , biology , biochemistry , genetics , mathematical analysis
Objective: We compared the pharmacokinetics of two methods for dosing gentamicin for the treatment of postpartum endometritis with the goal of achieving adequate peak serum concentrations (>12 mg/L) and prolonged trough levels below 2 mg/L