Open AccessFractional Flow Reserve following Percutaneous Coronary Intervention
Author(s) -
Udit Thakur,
Nancy Khav,
A. Comella,
Michael Michail,
Abdul Rahman Ihdayhid,
Eric Poon,
Stephen J. Nicholls,
Brian Ko,
Adam Brown
Publication year - 2020
Publication title -
journal of interventional cardiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.764
H-Index - 51
eISSN - 1540-8183
pISSN - 0896-4327
DOI - 10.1155/2020/7467943
Subject(s) - fractional flow reserve , conventional pci , medicine , percutaneous coronary intervention , cardiology , restenosis , stent , revascularization , coronary angiography , radiology , myocardial infarction
Fractional flow reserve (FFR) is routinely used to determine lesion severity prior to percutaneous coronary intervention (PCI). However, there is an increasing recognition that FFR may also be useful following PCI to identify mechanisms leading to restenosis and the need for repeat revascularization. Post-PCI FFR is associated with the presence and severity of stent under-expansion and may help identify peri-stent-related complications. FFR pullback may also unmask other functionally significant lesions within the target vessel that were not appreciable on angiography. Recent studies have confirmed the prognostic utility of performing routine post-PCI FFR and suggest possible interventional targets that would improve stent durability. In this review, we detail the theoretical basis underlying post-PCI FFR, provide practical tips to facilitate measurement, and discuss the growing evidence supporting its use.