Open AccessKetamine-xylazine anesthesia depth affects auditory neuronal responses in the lateral superior olive complex of the gerbil
Author(s) -
Zhizi Jing,
Michael Pecka,
Benedikt Grothe
Publication year - 2021
Publication title -
journal of neurophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.302
H-Index - 245
eISSN - 1522-1598
pISSN - 0022-3077
DOI - 10.1152/jn.00217.2021
Subject(s) - xylazine , ketamine , gerbil , brainstem , neuroscience , anesthesia , premovement neuronal activity , medicine , psychology , ischemia , cardiology
We studied how the depth of ketamine-xylazine anesthesia altered response properties of lateral superior olive complex neurons, and auditory brainstem evoked responses. Our results provide direct evidence that anesthesia depth affects auditory neuronal responses and reinforce the notion that both the anesthetics and the anesthesia depth should be considered when interpreting/comparing in vivo neuronal recordings.