Leucine augments specific skeletal muscle mitochondrial respiratory pathways during recovery following 7 days of physical inactivity in older adults | Zendy

Emily ArentsonLantz | Zendy; Jasmine Mikovic | Zendy; Nisha Bhattarai | Zendy; Christopher S. Fry | Zendy; Séverine Lamon | Zendy; Craig Porter | Zendy; Douglas PaddonJones | Zendy

Open Access

Leucine augments specific skeletal muscle mitochondrial respiratory pathways during recovery following 7 days of physical inactivity in older adults

Author(s) -

Emily ArentsonLantz,

Jasmine Mikovic,

Nisha Bhattarai,

Christopher S. Fry,

Séverine Lamon,

Craig Porter,

Douglas PaddonJones

Publication year - 2021

Publication title -

journal of applied physiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.253

H-Index - 229

eISSN - 8750-7587

pISSN - 1522-1601

DOI - 10.1152/japplphysiol.00810.2020

Subject(s) - skeletal muscle , leucine , respiration , oxidative stress , endocrinology , mitochondrion , respiratory system , medicine , sarcopenia , insulin sensitivity , biology , diabetes mellitus , anatomy , insulin resistance , biochemistry , amino acid

In older adults, leucine mitigated the loss of insulin sensitivity associated with muscular disuse. Leucine supplementation increased mitochondrial respiration and reduced a marker of oxidative stress following periods of disuse and rehabilitation.

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