Open AccessEffect of respiratory rate and size of cannula on pressure and dead-space clearance during nasal high flow in patients with COPD and acute respiratory failure
Author(s) -
Maximilian I Pinkham,
U Domanski,
KJ Franke,
Justus Hartmann,
Maik Schroeder,
T. Williams,
Georg Nilius,
Stanislav Tatkov
Publication year - 2022
Publication title -
journal of applied physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.253
H-Index - 229
eISSN - 8750-7587
pISSN - 1522-1601
DOI - 10.1152/japplphysiol.00769.2021
Subject(s) - dead space , medicine , anesthesia , cannula , expiration , respiratory rate , respiratory system , nasal cannula , ventilation (architecture) , copd , respiratory failure , mechanical ventilation , surgery , heart rate , blood pressure , mechanical engineering , engineering
During nasal high flow (NHF) an increased breathing frequency, which is commonly observed in acute respiratory failure, can lead to decreased dead-space clearance. Higher NHF rates increase the clearance and reduce the rebreathing which may eventually lower the respiratory rate and the work of breathing. Monitoring of the respiratory rate could be an important indicator of not only the respiratory function but also the NHF rate selection and the therapy efficacy.