Postexercise urinary alpha-1 acid glycoprotein is not dependent on hypoxia | Zendy

Kelsey E. Joyce | Zendy; George M. Balanos | Zendy; Christopher Bradley | Zendy; Amy Fountain | Zendy; A.R. Bradwell | Zendy; Samuel J. E. Lucas | Zendy

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Postexercise urinary alpha-1 acid glycoprotein is not dependent on hypoxia

Author(s) -

Kelsey E. Joyce,

George M. Balanos,

Christopher Bradley,

Amy Fountain,

A.R. Bradwell,

Samuel J. E. Lucas

Publication year - 2021

Publication title -

journal of applied physiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.253

H-Index - 229

eISSN - 8750-7587

pISSN - 1522-1601

DOI - 10.1152/japplphysiol.00476.2021

Subject(s) - medicine , hypoxemia , endocrinology , hypoxia (environmental) , excretion , vo2 max , urinary system , albumin , heart rate , physical exercise , proteinuria , chemistry , blood pressure , kidney , oxygen , organic chemistry

By superimposing hypoxic exposure and maximal exercise, we were able to investigate the impact of hypoxia on postexercise proteinuria. Urinalysis for α1-AGP (via particle-enhanced immunoturbidimetry) in specimens collected pre-/postexercise enabled the sensitive detection of altered glomerular permeability. Data indicated that exercise intensity, rather than the degree of exercise-induced hypoxemia, determines postexercise proteinuria.

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